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Below are publications that have resulted from Array's proprietary research programs or through research collaborations with other biotechnology or pharmaceutical companies. The links for the articles go to subscription-based sites and may require a fee to view the article.
Bioorganic & Medicinal Chemistry Letters
8/8/2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: Synthesis and optimization studies of benzothiazine-substituted tetramic acids
Javier de Vicente, et al.
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Bioorganic & Medicinal Chemistry Letters
8/8/2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: Structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides
Javier de Vicente, et al.
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Journal of Translational Medicine
7/20/2009
KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells
Ki Hyung Kim, et al.
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Leukemia
5/21/2009
Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells
BZ Carter, et al.
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Bioorganic & Medicinal Chemistry Letters
5/7/2009
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure–activity relationships of benzothiazine-substituted quinolinediones
Javier de Vicente, et al.
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Bioorganic & Medicinal Chemistry Letters
5/3/2009
Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors
Robert T. Hendricks, et al.
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Biochemistry
2/11/2009
Inhibition and Binding Kinetics of the Hepatitis C Virus NS3 Protease Inhibitor ITMN-191 Reveals Tight Binding and Slow Dissociative Behavior
Ravi Rajagopalan, et al.
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Bioorganic & Medicinal Chemistry Letters
1/30/2009
3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase
Robert T. Hendricks, et al.
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